Journal of Biomechanics
Volume 35, Issue 9 , Pages 1285-1290 , September 2002

Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage

  • Charlene M. Flahiff

      Affiliations

    • Department of Biomedical Engineering, Duke University, Box 90281, 136 Hudson Hall, Durham, NC 22708-0281, USA
    • ,
  • Daria A. Narmoneva

      Affiliations

    • Department of Mechanical Engineering, Massachusetts Institute of Technology, Boston, MA, USA
    • ,
  • Janet L. Huebner

      Affiliations

    • Department of Medicine, Division of Rheumatology, Allergy, & Clinical Immunology, Duke University Medical Center, Durham, NC, USA
    • ,
  • Virginia B. Kraus

      Affiliations

    • Department of Medicine, Division of Rheumatology, Allergy, & Clinical Immunology, Duke University Medical Center, Durham, NC, USA
    • ,
  • Farshid Guilak

      Affiliations

    • Department of Surgery, Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA
    • ,
  • Lori A. Setton

      Affiliations

    • Department of Biomedical Engineering, Duke University, Box 90281, 136 Hudson Hall, Durham, NC 22708-0281, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-919-660-5131; fax: +1-919-660-5362

,Accepted 22 February 2002.

References 

  1. Akizuki S, Mow VC, Muller F, Pita JC, Howell DS, Manicourt DH. Tensile properties of human knee joint cartilage: I. Influence of ionic conditions, weight bearing, and fibrillation on the tensile modulus. Journal of Orthopaedic Research. 1986;4:379–392
  2. Athanasiou KA, Rosenwasser MP, Buckwater JA, Malinin TI, Mow VC. Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilage. Journal of Orthopaedic Research. 1991;9:330–340
  3. Athanasiou KA, Zhu CF, Wang X, Agrawal CM. Effects of aging and dietary restriction on the structural integrity of rat articular cartilage. Annals of Biomedical Engineering. 2000;28:143–149
  4. Bendele AM, White SL, Hulman JF. Osteoarthrosis in guinea pigs (histopathologic and scanning electron microscope features). Laboratory Animal Science. 1989;39:115–121
  5. Eisenberg S, Grodzinsky A. Swelling of articular cartilage and other connective tissues (electromechanochemical forces). Journal of Orthopaedic Research. 1985;3:148–159
  6. Elliott DM, Guilak F, Vail TP, Wang JY, Setton LA. Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis. Journal of Orthopaedic Research. 1999;17:503–508
  7. Elliott DM, Narmoneva DA, Setton LA. Direct measurement of the poisson's ratio of human articular cartilage in tension (the effects of depth, age and degeneration). Journal of Biomechanical Engineering. 2002;124:223–228
  8. Guilak F, Ratclifffe A, Lane N, Rosenwasser MP, Mow VC. Mechanical and biochemical changes in the superficial zone of articular cartilage in canine experimental osteoarthritis. Journal of Orthopaedic Research. 1994;12:474–484
  9. Hayes WC, Mockros LF. Viscoelastic properties of human articular cartilage. Journal of Applied Physiology. 1971;31:562–568
  10. Kempson GE. Relationship between the tensile properties of articular cartilage from the human knee and age. Annals of the Rheumatic Diseases. 1982;41:508–511
  11. Kempson GE. Age-related changes in the tensile properties of human articular cartilage (a comparative study between the femoral head of the hip joint and the talus of the ankle joint). Biochimica et Biophysica Acta. 1991;1075:223–230
  12. Lai WM, Hou JS, Mow VC. A triphasic theory for the swelling and deformation behaviors of articular cartilage. Journal of Biomechanical Engineering. 1991;113:245–258
  13. LeRoux MA, Arokoski J, Vail TP, Guilak F, Hyttinen MM, Kiviranta I, et al. Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. Journal of Orthopaedic Research. 2000;18:383–392
  14. Lillie RD. Histopathologic Technic and Practical Histochemistry. New York: McGraw-Hill Book Company; 1954;
  15. Maroudas A. Balance between swelling pressure and collagen tension in normal and degenerate cartilage. Nature. 1976;260:808–809
  16. Maroudas A, Bannon C. Measurement of swelling pressure in cartilage and comparison with the osmotic pressure of constituent proteoglycans. Biorheology. 1981;18:619–632
  17. Martin I, Obradovic B, Freed LE, Vunjak-Novakovic G. Method for quantitative analysis of glycosaminoglycan distribution in cultured natural and engineered cartilage. Annals of Biomedical Engineering. 1999;27:656–662
  18. Narmoneva DA, Cheung HS, Wang JY, Howell DS, Setton LA. Altered swelling behavior of femoral cartilage following joint immobilization in a canine model. Journal of Orthopaedic Research. 2002;20:83–91
  19. Narmoneva DA, Wang JY, Setton LA. Nonuniform swelling-induced residual strains in articular cartilage. Journal of Biomechanics. 1999;32:401–408
  20. Narmoneva DA, Wang JY, Setton LA. A non-contacting method for material property determination for articular cartilage from osmotic loading. Biophysical Journal. 2001;81:3066–3076
  21. Roth V, Mow VC. The intrinsic tensile behavior of the matrix of bovine articular cartilage and its variation with age. Journal of Bone and Joint Surgery. 1980;62:1102–1117
  22. Schinagl RM, Ting MK, Price JH, Sah RL. Video microscopy to quantitate the inhomogeneous equilibrium strain within articular cartilage during confined compression. Annals of Biomedical Engineering. 1996;24:500–512
  23. Setton LA, Mow VC, Muller FJ, Pita JC, Howell DS. Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament. Journal of Orthopaedic Research. 1994;12:451–463
  24. Setton LA, Gu W, Lai MW, Mow VC. Mechanics of Poroelastic Media. Boston: Kluwer-Academic Publishers; 1995;
  25. Setton LA, Mow VC, Howell DS. Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament. Journal of Orthopaedic Research. 1995;13:473–482
  26. Soltz MA, Ateshian GA. A conewise linear elasticity mixture model for the analysis of tension-compression nonlinearity in articular cartilage. Journal of Biomechanical Engineering. 2000;122:576–586
  27. Sun, D.N., Guo, G.E., Lai, W.M., Mow, V.C., 1999. A triphasic analysis of indentation on articular cartilage. 1999 Advances in Bioengineering, ASME BED-43, 217–218.
  28. Woo SL-Y, Akeson WH, Jemmott GF. Measurement of nonhogeneous, directional mechanical properties of articular cartilage in tension. Journal of Biomechanics. 1976;9:785–791
  29. Woo SL-Y, Simon BR, Kuei SC, Akeson WH. Quasi-linear viscoelastic properties of normal articular cartilage. Journal of Biomechanical Engineering. 1980;102:85–90

PII: S0021-9290(02)00079-9

Journal of Biomechanics
Volume 35, Issue 9 , Pages 1285-1290 , September 2002

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