Journal of Biomechanics
Volume 38, Issue 9 , Pages 1770-1779 , September 2005

Mechanical properties of native and ex vivo remodeled porcine saphenous veins

  • Rebecca J. Gusic

      Affiliations

    • The Institute for Medicine and Engineering, Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
    • ,
  • Matus Petko

      Affiliations

    • Department of Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA
    • ,
  • Richard Myung

      Affiliations

    • Department of Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA
    • ,
  • J. William Gaynor

      Affiliations

    • Department of Cardiothoracic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA
    • ,
  • Keith J. Gooch

      Affiliations

    • The Institute for Medicine and Engineering, Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +12155732786; fax: +12155736815.

,Accepted 6 April 2005.

References 

  1. Abbott WM, Megerman J, Hasson JE, L’Italien G, Warnock DF. Effect of compliance mismatch on vascular graft patency. Journal of Vascular Surgery. 1987;5(2):376–382
  2. Baumbach GL, Dobrin PB, Hart MN, Heistad DD. Mechanics of cerebral arterioles in hypertensive rats. Circulation Research. 1988;62:56–64
  3. Bund SJ. Spontaneously hypertensive rat resistance artery structure related to myogenic and mechanical properties. Clinical Science. 2001;101:385–393
  4. Canver CC. Conduit options in coronary artery bypass surgery. Chest. 1995;108:1150–1155
  5. Chesler NC, Ku DN, Galis ZS. Transmural pressure induces matrix-degrading activity in porcine arteries ex vivo. American Journal of Physiology-Heart and Circulatory Physiology. 1999;277(5):H2002–H2009
  6. Cholley BP, Lang RM, Korcarz CE, Shroff SG. Smooth muscle relaxation and local hydrzulic impedance properties of the aorta. Journal of Applied Physiology. 2001;90(6):2427–2438
  7. Clerin V, Gusic RJ, O’Brien R, Kirshbom PM, Myung RJ, Gaynor JW, et al. Mechanical environment, donor age, and presence of endothelium interact to modulate porcine artery viability ex vivo. Annals of Biomedical Engineering. 2002;30(9):1117–1127
  8. Clerin V, Nichol J, Petko M, Myung RJ, Gaynor JW, Gooch KJ. Tissue engineering of arteries by directed remodeling of intact arterial segments. Tissue Engineering. 2003;9(3):461–472
  9. Cox RH. Comparison of carotid artery mechanics in the rat, rabbit, and dog. American Journal of Physiology. 1978;234(3):H280–H288
  10. Davies AH, Magee TR, Baird RN, Sheffield E, Horrocks M. Vein compliance: a preoperative indicator of vein morphology and of veins at risk of vascular graft stenosis. British Journal of Surgery. 1992;79(10):1019–1021
  11. Dobrin PB, Littooy FN, Golan J, Blakeman B, Fareed J. Mechanical and histologic changes in canine vein grafts. Journal of Surgical Research. 1988;44:259–265
  12. Dobrin PB, Littooy FN, Endean ED. Mechanical factors predisposing to intimal hyperplasia and medial thickening in autogenous vein grafts. Surgery. 1989;105:393–400
  13. Fridez P, Rachev A, Meister JJ, Hayashi K, Stergiopulos N. Model of geometrical and smooth muscle tone adaptation of carotid artery subject to step change in pressure. American Journal of Physiology-Heart and Circulatory Physiology. 2001;280:H2752–2760
  14. Gusic, R.J., Myung, R., Petko, M., Gaynor, J.W., Gooch, K.J., 2005. Mechanical properties of native and ex vivo remodeled porcine saphenous veins. Journal of Biomechanics, in press, doi:10.1016/j.biomech.2005.04.002.
  15. Intengan HD, Schiffrin EL. Structure and mechanical properties of resistance arteries in hypertension. Hypertension. 2000;36:312–318
  16. Lawrence AR, Gusic RJ, Gooch KJ. Noninvasive determination of perfused artery dimensions ex vivo using a pressure-diameter relationship. Biorheology. 2003;40(5):523–529
  17. Mavromatis K, Fukai T, Tate M, Chesler N, Ku DN, Galis ZS. Early effects of arterial hemodynamic conditions on human saphenous veins perfused ex vivo. Arteriosclerosis Thrombosis and Vascular Biology. 2000;20:1889–1895
  18. Mourad JJ, Girerd X, Boutouyrie P, Safar M, Laurent S. Opposite effects of remodeling and hypertrophy on arterial compliance in hypertension. Hypertension. 1998;31(part 2):529–533
  19. Nichol, J.W., Petko, M., Myung, R.J., Gaynor, J.W., Gooch, K.J. Hemodynamic conditions modulate the growth, remodeling, and mechanical properties of arteries subjected to increased axial loading ex vivo. Annals of Biomedical Engineering, in press.
  20. Rachev A, Stergiopulos N, Meister JJ. A model for geometric and mechanical adaptation of arteries to sustained hypertension. Journal of Biomechanical Engineering. 1998;120:9–17
  21. Schwartz LB, O’Donohoe MK, Purut CM, Mikat EM, Hagen P, McCann RL. Myointimal thickening in experimental vein grafts is dependent on wall tension. Journal of Vascular Surgery. 1992;25:176–186
  22. Wendling WW, Krasner LJ, Cooper SC, Chen D, Harakal C, Addonizio VP, et al. Effects of stretch or distention on phenylephrine-induced constriction of human coronary artery bypass grafts. Journal of Cardiothoracic and Vascular Anesthesia. 2001;15(6):717–722
  23. Zanchi A, Stergiopulos N, Brunner HR, Hayoz D. Differences in the mechanical properties of the rat carotid artery in vivo, in situ, and in vitro. Hypertension. 1998;32:180–185

PII: S0021-9290(05)00165-X

doi: 10.1016/j.jbiomech.2005.04.002

Journal of Biomechanics
Volume 38, Issue 9 , Pages 1770-1779 , September 2005

Article Tools

* Image Usage & Resolution