Journal of Biomechanics
Volume 42, Issue 3 , Pages 257-260 , 9 February 2009

Permeability evaluation of 45S5 Bioglass®-based scaffolds for bone tissue engineering

  • Ignacio Ochoa

      Affiliations

    • Aragon Institute of Engineering Research (I3A), Group of Structural Mechanics and Materials Modelling (GEMM), Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Universidad de Zaragoza, 50018 Zaragoza, Spain
    • ,
  • José A. Sanz-Herrera

      Affiliations

    • Aragon Institute of Engineering Research (I3A), Group of Structural Mechanics and Materials Modelling (GEMM), Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Universidad de Zaragoza, 50018 Zaragoza, Spain
    • ,
  • José M. García-Aznar

      Affiliations

    • Aragon Institute of Engineering Research (I3A), Group of Structural Mechanics and Materials Modelling (GEMM), Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Universidad de Zaragoza, 50018 Zaragoza, Spain
    • ,
  • Manuel Doblaré

      Affiliations

    • Aragon Institute of Engineering Research (I3A), Group of Structural Mechanics and Materials Modelling (GEMM), Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Universidad de Zaragoza, 50018 Zaragoza, Spain
    • ,
  • Darmawati Mohamad Yunos

      Affiliations

    • Department of Materials, Imperial College London, South Kensington Campus, London SW7 2BP, UK
    • ,
  • Aldo R. Boccaccini

      Affiliations

    • Department of Materials, Imperial College London, South Kensington Campus, London SW7 2BP, UK
    • Corresponding Author InformationCorresponding author. Tel.: +442075946731.

,Accepted 29 October 2008.

References 

  1. Boccaccini AR, Chen QZ, Lefebvre L, Gremillard L, Chevalier J. Sintering, crystallisation and biodegradation behaviour of Bioglass®-derived glass-ceramics. Faraday Discuss. 2007;136:27–44
  2. Botchwey E, Dupree MA, Pollack SR, Levine EM, Laurencin CT. Tissue engineered bone: measurement of nutrient transport in three-dimensional matrices. J. Biomed. Mater. Res. A. 2003;67A:357–367
  3. Chan G, Mooney DJ. New materials for tissue engineering: towards greater control over the biological response. Trends Biotechnol. 2008;26:382–392
  4. Chen QZ, Boccaccini AR. Coupling mechanical competence and bioresorbability in Bioglass®-derived tissue engineering scaffolds. Adv. Eng. Mater. 2006;8:285–289
  5. Chen QZ, Thompson ID, Boccaccini AR. 45S5 Bioglass®-derived glass-ceramic scaffolds for bone tissue engineering. Biomaterials. 2006;27:2414–2425
  6. Chen QZ, Efthymiou A, Salih V, Boccaccini AR. Bioglass®-derived glass-ceramic scaffolds: study of cell proliferation and scaffold degradation in vitro. J. Biomed. Mater. Res. A. 2008;84A:1049–1060
  7. Day RM, Boccaccini AR, Shurey S, Roether JA, Forbes A, Hench LL, et al. Assessment of polyglycolic acid mesh and bioactive glass for soft-tissue engineering scaffolds. Biomaterials. 2004;25:5857–5866
  8. Discher DE, Janmey P, Wang YL. Tissue cells feel and respond to the stiffness of their substrate. Science. 2005;310:1139–1143
  9. Grimm MJ, Williams JL. Measurements of permeability in human calcaneal trabecular bone. J. Biomech. 1997;30:743–745
  10. Guarino V, Causa F, Ambrosio L. Bioactive scaffolds for bone and ligament tissue. Expert Rev. Med. Devices. 2007;4(3):405–418
  11. Haddock SM, Debes JC, Nauman EA, Fong KE, Arramon YP, Keaveny TM. Structure–function relationships for coralline hydroxyapatite bone substitute. J. Biomed. Mater. Res. 1999;47:71–78
  12. Haugen H, Will J, Kohler A, Hopfner U, Aigner J, Wintermantel E. Ceramic TiO2-foams: characterisation of a potential scaffolds. J. Eur. Ceram. Soc. 2004;24:661–668
  13. Hutmacher DW, Schantz JT, Lam CXF, Tan KC, Lim TC. State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective. J. Tissue Eng. Regenerative Med. 2007;1:245–260
  14. Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials. 2005;27:5474–5491
  15. Kohles SS, Roberts JB, Upton ML, Wilson CG, Bonassar LJ, Schlichting AL. Direct perfusion measurements of cancellous bone anisotropic permeability. J. Biomech. 2001;34:1197–1202
  16. Langer R, Vacanti JP. Tissue engineering. Science. 1993;260:920–926
  17. Li S, De Wijn JR, Li J, Layrolle P, De Groot K. Macroporous biphasic calcium phosphate scaffolds with high permeability/porosity ratio. Tissue Eng. 2003;9:535–546
  18. Maxwell VC, Wei L. A Permeability measurement system for tissue engineering scaffolds. Meas. Sci. Technol. 2007;18:208–216
  19. Muthutantri, A., Huang, J., Edirisinghe, M., 2008. Novel preparation of graded porous structures for medical engineering, J. R. Soc. Interface, 10.1098/rsif.2008.0092, in press.
  20. Nauman EA, Fong KE, Keaveny TM. Dependence of intertrabecular permeability on flow direction and anatomic site. Ann. Biomed. Eng. 1999;27:517–524
  21. Sanz-Herrera JA, Kasper C, van Griensven M, Garcia-Aznar JM, Ochoa I, Doblare M. Mechanical and flow characterization of Sponceram® carriers: Evaluation by homogenization theory and experimental validation, J. Biomed. Mater. Res. B. 2008;87:42–48
  22. Sanz-Herrera JA, Garcia-Aznar JM, Doblare M. A mathematical model for bone tissue regeneration inside a specific type of scaffold. Biomech. Model Mechan. 2008;7:355–366
  23. Scheidegger AE. The Physics of Flow Through Porous Media. Toronto, Canada: Press; 1974;
  24. Sell S, Barnes C, Simpson D, Bowlin G. Scaffold permeability as a means to determine fiber diameter and pore size of electrospun fibrinogen. J. Biomed. Mater. Res. A. 2008;85A:115–116
  25. Shimko DA, Shimko VF, Sander EA, Dickson KF, Nauman EA. Effect of porosity on the fluid flow characteristics and mechanical properties of tantalum scaffolds. J. Biomed. Mater. Res. B. 2005;73:315–324
  26. Swider P, Conroy M, Pedrono A, Ambard D, Mantell S, Soballe K, et al. Use of high-resolution MRI for investigation of fluid flow and global permeability in a material with interconnected porosity. J. Biomech. 2007;40:2112–2118
  27. Vitale-Brovarone C, Verne E, Robiglio L, Appendino P, Bassi F, Martinasso G, et al. Development of glass-ceramic scaffolds for bone tissue engineering: characterisation, proliferation of human osteoblasts and nodule formation. Acta Biomater. 2007;3:199–208
  28. Wu C, Ramaswamy Y, Boughton P, Zreiqat H. Improvement of mechanical and biological properties of porous CaSiO3 scaffolds by poly(d,l-lactic acid) modification. Acta Biomater. 2008;4:343–353
  29. Xynos ID, Edgar AJ, Buttery LDK, Hench LL, Polak JM. Gene expression profiling of human osteoblasts following treatment with the ionic products of Bioglass® 45S5 dissolution. J. Biomed. Mater. Res. 2001;55:151–159

PII: S0021-9290(08)00556-3

doi: 10.1016/j.jbiomech.2008.10.030

Journal of Biomechanics
Volume 42, Issue 3 , Pages 257-260 , 9 February 2009

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