Journal of Biomechanics
Volume 43, Issue 12 , Pages 2267-2273 , 26 August 2010

Validation of theoretical framework explaining active solute uptake in dynamically loaded porous media

,Accepted 30 April 2010.

References 

  1. Albro MB, Chahine NO, Li R, Yeager K, Hung CT, Ateshian GA. Dynamic loading of deformable porous media can induce active solute transport. J. Biomech. 2008;41:3152–3157
  2. Albro MB, Rajan V, Li R, Hung CT, Ateshian GA. Characterization of the concentration-dependence of solute diffusivity and partitioning in a model dextran–agarose transport system. Cell Mol. Bioeng. 2009;2:295–305
  3. Ateshian GA, Likhitpanichkul M, Hung CT. A mixture theory analysis for passive transport in osmotic loading of cells. J. Biomech. 2006;39:464–475
  4. Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB. Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J. Cell Sci. 1995;108(Part 4):1497–1508
  5. Buschmann MD, Gluzband YA, Grodzinsky AJ, Kimura JH, Hunziker EB. Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix. J. Orthop. Res. 1992;10:745–758
  6. Chahine NO, Albro MB, Lima EG, Wei VI, Dubois CR, Hung CT, et al. Effect of dynamic loading on the transport of solutes into agarose hydrogels. Biophys. J. 2009;97:968–975
  7. Crank J. The Mathematics of Diffusion.. Oxford, England: Clarendon Press; 1979;
  8. Deen WM. Hindered transport of large molecules in liquid-filled pores. AIChE Journal. 1987;33:1409–1425
  9. Evans RC, Quinn TM. Solute convection in dynamically compressed cartilage. J. Biomech. 2006;39:1048–1055
  10. Ferry JD. Statistical evaluation of sieve constants in ultrafiltration. J. Gen. Physiol. 1936;20:95–104
  11. Fick A. Über Diffusion. Ann. Phys. 1855;94:59–86
  12. Gu WY, Yao H, Huang CY, Cheung HS. New insight into deformation-dependent hydraulic permeability of gels and cartilage, and dynamic behavior of agarose gels in confined compression. J. Biomech. 2003;36:593–598
  13. Huang AH, Yeger-McKeever M, Stein A, Mauck RL. Tensile properties of engineered cartilage formed from chondrocyte- and MSC-laden hydrogels. Osteoarthritis Cartilage. 2008;16:1074–1082
  14. Johnson EM, Berk DA, Jain RK, Deen WM. Diffusion and partitioning of proteins in charged agarose gels. Biophys. J. 1995;68:1561–1568
  15. Johnson EM, Berk DA, Jain RK, Deen WM. Hindered diffusion in agarose gels: test of effective medium model. Biophys. J. 1996;70:1017–1023
  16. Kosto KB, Deen WM. Hindered convection of macromolecules in hydrogels. Biophys. J. 2005;88:277–286
  17. Laurent TC, Killander J. A theory of gel filtration and its experimental verification. J. Chromatogr. 1964;14:317–330
  18. Lazzara MJ, Deen WM. Effects of concentration on the partitioning of macromolecule mixtures in agarose gels. J. Colloid Interface Sci. 2004;272:288–297
  19. Lebrun L, Junter GA. Diffusion of sucrose and dextran through agar gel membranes. Enzyme Microb. Technol. 1993;15:1057–1062
  20. Leddy HA, Awad HA, Guilak F. Molecular diffusion in tissue-engineered cartilage constructs: effects of scaffold material, time, and culture conditions. J. Biomed. Mater. Res. B Appl. Biomater. 2004;70:397–406
  21. Leddy HA, Guilak F. Site-specific molecular diffusion in articular cartilage measured using fluorescence recovery after photobleaching. Ann. Biomed. Eng. 2003;31:753–760
  22. Leddy HA, Guilak F. Site-specific effects of compression on macromolecular diffusion in articular cartilage. Biophys. J. 2008;95:4890–4895
  23. Leddy HA, Haider MA, Guilak F. Diffusional anisotropy in collagenous tissues: fluorescence imaging of continuous point photobleaching. Biophys. J. 2006;91:311–316
  24. Lee KY, Peters MC, Anderson KW, Mooney DJ. Controlled growth factor release from synthetic extracellular matrices. Nature. 2000;408:998–1000
  25. Mauck RL, Hung CT, Ateshian GA. Modeling of neutral solute transport in a dynamically loaded porous permeable gel: implications for articular cartilage biosynthesis and tissue engineering. J. Biomech. Eng. 2003;125:602–614
  26. Mauck RL, Soltz MA, Wang CC, Wong DD, Chao PH, Valhmu WB, et al. Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J. Biomech. Eng. 2000;122:252–260
  27. O’Driscoll SW, Fitzsimmons JS, Commisso CN. Role of oxygen tension during cartilage formation by periosteum. J. Orthop. Res. 1997;15:682–687
  28. O’Hara BP, Urban JP, Maroudas A. Influence of cyclic loading on the nutrition of articular cartilage. Ann. Rheum. Dis. 1990;49:536–539
  29. Perry PA, Fitzgerald MA, Gilbert RG. Fluorescence recovery after photobleaching as a probe of diffusion in starch systems. Biomacromolecules. 2006;7:521–530
  30. Pluen A, Netti PA, Jain RK, Berk DA. Diffusion of macromolecules in agarose gels: comparison of linear and globular configurations. Biophys. J. 1999;77:542–552
  31. Shearn JT, Juncosa-Melvin N, Boivin GP, Galloway MT, Goodwin W, Gooch C, et al. Mechanical stimulation of tendon tissue engineered constructs: effects on construct stiffness, repair biomechanics, and their correlation. J. Biomech. Eng. 2007;129:848–854
  32. Sittinger M, Perka C, Schultz O, Haupl T, Burmester GR. Joint cartilage regeneration by tissue engineering. Z. Rheumatol. 1999;58:130–135
  33. Soltz MA, Ateshian GA. A conewise linear elasticity mixture model for the analysis of tension-compression nonlinearity in articular cartilage. J. Biomech. Eng. 2000;122:576–586
  34. Urciuolo F, Imparato G, Netti PA. Effect of dynamic loading on solute transport in soft gels implication for drug delivery. AIChE J. 2008;54:824–834
  35. Wang L, Cowin SC, Weinbaum S, Fritton SP. Modeling tracer transport in an osteon under cyclic loading. Ann. Biomed. Eng. 2000;28:1200–1209

PII: S0021-9290(10)00268-X

doi: 10.1016/j.jbiomech.2010.04.041

Journal of Biomechanics
Volume 43, Issue 12 , Pages 2267-2273 , 26 August 2010

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