Journal of Biomechanics
Volume 45, Issue 5 , Pages 780-789, 15 March 2012

Osmotic swelling and residual stress in cardiovascular tissues

  • Yoram Lanir

      Affiliations

    • Corresponding Author InformationTel.: +972 4 8294113; fax: +972 4 8294599.

Faculty of Biomedical Engineering, Technion—Israel Institute of Technology, Haifa 32000, Israel

Accepted 1 July 2011. published online 11 January 2012.

Abstract 

Osmotic swelling (OS) and residual stress (RS) significantly affect the function of cardiovascular (CVS) tissues and organs. The physical mechanisms of OS and RS are reviewed and analyzed with focus on the theoretical background and related experimental evidence. It will be shown that swelling of CVS tissues stems from the presence of charged proteoglycan macro-molecules in these tissues, and that this swelling is a key determinant of RS. In view of OS and RS functional significance in mechanical function, modeling attempts which incorporate them in CVS stress analysis will be presented and discussed.

Keywords: Cardiovascular tissues, Osmotic swelling, Residual stress, Stress analysis, Structural constitutive law

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PII: S0021-9290(11)00700-7

doi:10.1016/j.jbiomech.2011.11.018

Journal of Biomechanics
Volume 45, Issue 5 , Pages 780-789, 15 March 2012